Airway pressure release ventilation during ex vivo lung perfusion attenuates injury
نویسندگان
چکیده
منابع مشابه
Other approaches to open-lung ventilation: airway pressure release ventilation.
OBJECTIVE To review the use of airway pressure release ventilation (APRV) in the treatment of acute lung injury/acute respiratory distress syndrome. DATA SOURCE Published animal studies, human studies, and review articles of APRV. DATA SUMMARY APRV has been successfully used in neonatal, pediatric, and adult forms of respiratory failure. Experimental and clinical use of APRV has been shown ...
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Objective(s): Asiaticoside (AS) displays anti-inflammation, and anti-apoptosis effect, but the role of AS in hyperoxia-induced lung injury (HILI) treatment is undefined. Therefore, the aim of this study was to investigate the effects of AS on HILI on premature rats and alveolar type II (AEC II) cells.Materials and Methods: Sprague-Dawley...
متن کاملRegional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury
INTRODUCTION There is an increasing interest in biphasic positive airway pressure with spontaneous breathing (BIPAP+SBmean), which is a combination of time-cycled controlled breaths at two levels of continuous positive airway pressure (BIPAP+SBcontrolled) and non-assisted spontaneous breathing (BIPAP+SBspont), in the early phase of acute lung injury (ALI). However, pressure support ventilation ...
متن کاملAirway pressure release ventilation and successful lung donation.
HYPOTHESIS Donor management with airway pressure release ventilation (APRV) improves oxygenation and increases lung donation while maintaining equivalent graft survival. DESIGN Retrospective case series. SETTING Private, tertiary care, level I trauma center. PATIENTS Forty-five consecutive organ donors. INTERVENTIONS Management with assist/control ventilation (ACV) or APRV. MAIN OUTCO...
متن کاملEarly airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury.
Acute respiratory distress syndrome (ARDS) afflicts 200,000 patients annually with a mortality rate of 30% to 60% despite wide use of low tidal volume (LTV) ventilation, the present standard of care. High-permeability alveolar edema and instability occur early in the development of ARDS, before clinical signs of lung injury, and represent potential targets for therapy. We hypothesize that early...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2017
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2016.09.029